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Current workflows useful for determining the MOA of novel compounds normally contain an variety of functional screening assays incorporating a myriad of isolated biological targets. These procedures generally do not file function within the dynamic environment through which these targets normally reside. This is especially essential for ion channel
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“The apprehension with applying non IID detailed ingredients is justified as it can be not possible To guage if FDA would locate the ‘novel excipient’ Safe and sound for use in a drug products as there isn't a outlined approach for analysis and approval of excipients. The FDA direction on ‘Nonclinical Scientific studies for the Safety Evalu